Quick answer
A first edition of The Principles and Practice of Medicine by William Osler (D. Appleton and Company, 1892) is identified by: First edition, first issue.
Checklist — a true first has these:
- First edition, first issueP-035522
- First-issue copies misspell Plato's dialogue Gorgias as 'Georgias' on the verso of the third leaf; this was corrected to 'Gorgias' only in the second printing of April 1892P-035523
- Within the first printing itself, the earliest copies carry publisher's advertisements dated November 1891, while later first-printing copies carry advertisements dated March 1892, making the November-1891-ad state the earliestP-035524
- Three thousand copies of the first printing sold within two months of publicationP-035525
- Publisher imprint reads D. Appleton and Company
- Not a book-club edition (see below)
| Author | William Osler |
|---|---|
| Publisher | D. Appleton and Company |
| Year | 1892 |
| True first | — |
| Format | Hardcover (trade) |
| Key point | First edition, first issue |
| Book-club edition exists? | — |
The points of issue
- First edition, first issue
- First-issue copies misspell Plato's dialogue Gorgias as 'Georgias' on the verso of the third leaf; this was corrected to 'Gorgias' only in the second printing of April 1892
- Within the first printing itself, the earliest copies carry publisher's advertisements dated November 1891, while later first-printing copies carry advertisements dated March 1892, making the November-1891-ad state the earliest
- Three thousand copies of the first printing sold within two months of publication
How D. Appleton and Company marked a first edition
- Numerical identification in parentheses/brackets at the FOOT OF THE LAST PAGE of text: '(1)' = first printing, '(2)' = second, etc.
- May occasionally have used a 'First Edition' statement instead of the foot-of-last-page number.
Full D. Appleton and Company first-edition guide →
How to verify your copy, step by step
- Find the copyright page — the verso (back) of the title page.
- Confirm the first-edition statement — look for “First Edition,” “First Printing,” or the publisher’s equivalent wording.
- Check for a number line or dated printing — the lowest number present is the printing; a dated first printing with no later printings listed is the tell.
- Rule out a book-club edition — a blind-stamp on the rear board or a jacket with no printed price marks a book-club copy.
- Photograph four things — the front cover, spine, title page, and copyright page — the standard record for identification.
The dust jacket
For a collectible first edition the dust jacket matters as much as the book. Confirm the jacket is present and unclipped — the printed price should still be at the corner of the flap (a clipped corner or a price-less flap can indicate a book-club issue). First-state jackets can differ from later ones in the cover art, blurbs, or review quotations; where a specific first-state jacket point is known for this title it is noted above.
Binding & format
Where multiple bindings exist, the hardcover trade issue is usually (but not always) the precedence copy — confirm against the points above. Later printings often show cheaper cloth, thinner boards, or simplified spine stamping. A simultaneous signed or limited issue, when one exists, is a distinct state from the trade first.
Frequently asked questions
Is my copy of The Principles and Practice of Medicine a first edition?
A first edition of The Principles and Practice of Medicine by William Osler (D. Appleton and Company) is identified by: First edition, first issue.
How do I tell the first printing from a later one?
Check the copyright page. A stated first edition, a number line ending in 1, or a dated first printing with no later printings listed is the key.
Is the book-club edition the same as the first?
No. Book-club editions reprint the text but are not the true first; look for a blind-stamp on the rear board or a jacket with no printed price.
I have a first edition of The Principles and Practice of Medicine — what should I do?
First, document the copy: photograph the copyright page (the number line and any edition statement) and the dust-jacket flap. Confirm the points of issue above against your copy, and decode the printing with the free First Edition Checker. Clearing out books? I take them as a free donation and make sure collectible copies are identified, not discarded: free pickup in the Albuquerque metro (scheduled by route), the 24/7 drop box at 5445 Edith Blvd NE, or donor-paid mail-in from anywhere in the US. Questions? Call or text 505-250-3804.
Glossary
- First edition
- Every copy printed from the first setting of type. Collectors usually want the first edition, first printing (the true first).
- First printing / impression
- A single press run from that setting. The first printing is the earliest and most desirable; later printings are still the first edition but not the true first.
- Number line (printer's key)
- A row of numbers on the copyright page (e.g. 10 9 8 7 6 5 4 3 2 1). The lowest number present is the printing — a line including 1 marks a first printing (Random House deliberately ends at 2).
- Points of issue
- Specific physical details — a stated edition, a number line, a typo, a jacket state — that identify the true first printing.
- Book-club edition (BCE)
- A reprint made for a book club. Tells include a blind-stamped dot or square on the rear board and a dust jacket with no printed price. Not the true first.
- First thus
- The first appearance of a particular version (first paperback, first illustrated, first U.S. printing) — a first of that kind, not the first edition of the work.
Related first editions
- Personal Narrative of Explorations and Incidents in Texas, New Mexico, California, Sonora, and Chihuahua — John Russell Bartlett
- Memoirs of General W. T. Sherman — William Tecumseh Sherman
- The Covered Wagon — Emerson Hough
- The Age of Innocence — Edith Wharton
- The Glimpses of the Moon — Edith Wharton
- Something New — P.G. Wodehouse
- Uneasy Money — P.G. Wodehouse
- The Red Badge of Courage: An Episode of the American Civil War — Stephen Crane
How to cite this page
New Mexico Literacy Project. “Is The Principles and Practice of Medicine by William Osler a First Edition? Points of Issue.” NMLP First-Edition Identification Reference. Reviewed 4 July 2026. Retrieved from https://newmexicoliteracyproject.org/first-edition/the-principles-and-practice-of-medicine. Licensed CC BY 4.0 — part of the open Canonical First-Edition Points of Issue dataset (DOI 10.5281/zenodo.21184548).